Proteins are necessary for the growth, building and recovery processes of the body. They are necessary for the functioning of the muscles and the skin and play an important role in the regulation of acidity and blood clotting. The body cannot use the proteins present in the diet. These proteins are therefore split into smaller particles called amino acids during digestion. So Amino acids are the building blocks of proteins. Man needs 22 different amino acids for the functioning of the body. These amino acids are subdivided into the essential, semi-essential and non-essential amino acids. The eight essential amino acids are the amino acids that have to be taken via diet (isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine).
The non-essential amino acids can be formed in the body from other amino acids if necessary. Semi-essential amino acids can also be formed in the body, but under certain circumstances this conversion will be insufficient. This group includes histidine, cysteine and arginine. Valine is also sometimes counted among the semi-essential amino acids.
Amino acid profile
With the help of an amino acid profile, one gets a good insight in various metabolic processes in a relatively simple way. Disorders in the functioning of, for example, the liver, intestines and kidneys can be detected. At the same time, insight is gained into any deficiencies that occur, which lead to disruptions in the amino acid metabolism.
A 24 hour urine collection is required for a reliable amino acid analysis. The urine is collected for one day in a urine container, to which a preservative has been added. A sample is taken from this urine and sent to the laboratory. At the results of the amino acid analysis an extensive explanation is given for a correct interpretation of the test. The result, with the explanation, is sent to the doctor and patient as soon as
When an amino acid analysis?
Many people have a hidden disorder in biochemistry, especially in amino acid metabolism. These disorders can lead to various symptoms. It can also lead to an increased risk of certain diseases, or they play a secondary role in a disease process. An example of this is an inhibition of methionine metabolism (heterozygous or hidden homocystinuria), which eventually causes occlusive vascular disease. This disorder would occur in 0.5-1.4% of the Western population. In addition to the application as health check-up, an amino acid analysis should be considered for the following diseases and symptoms:
– chronic fatigue, which does not change with conventional treatment
– frequent headache, migraine
– chronic gastrointestinal complaints or intestinal disorders
– intolerances to environmental factors, food or chemicals (MCS).
– frequent infections and chronic inflammatory processes.
– psychological complaints such as depression, schizophrenia
– learning disabilities
– hyperactive behavior
– malnutrition, lack of growth
– neurological abnormalities
– family history with degenerative diseases
Interpretations amino acid analysis
The blood values of essential amino acids reflect the food intake. If there are insufficient essential amino acids, the protein intake may be insufficient or the degradation of proteins is poor. Furthermore, there may be disorders that affect the permeability of the intestine. This can also be determined with a bowel permeability test.
Gastrointestinal disorders can be detected by studying the excretion of citrulline, homo citrulline and gamma-aminobutyric acid. The kidneys resorb the amino acids. If renal function decreases, certain amino acids increased in the urine will be excreted.
The conversions of certain amino acids from essential amino acids depend on certain vitamins and minerals. Deficiencies in zinc, magnesium, calcium, vitamins B1, B3, B6, folic acid and B12 can easily be established.
Inflammation causes a reduced secretion of certain amino acids.
For the second stage of liver function, sulphurous amino acids are required. In the analysis it can be determined whether these are sufficiently present.
The risk for cardiovascular disease can be determined by looking at the course of the biosynthetic pathway from methionine to taurine. A trim will eventually cause a secretion of homocystin.
Methylation disorders are also the basis of problems with stress management, blood pressure problems and the like. Furthermore, depression can be seen by paying attention to the ratio serine-glycine, the values for phenylalanine, tyrosine and tryptophan. Sleep disorders may also be due to reduced values.
Ammonia intoxication causes increased glutamine excretion. Concentration disorders and behavioral problems can be caused by this.
Finally, any inborn metabolic diseases can be discovered. Many of these diseases can occur without any noticeable symptoms, but make recovery difficult. For a good interpretation, you must send a clear description of your complaints, if possible together with laboratory results that are available.