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Allergiy and Intolerance

In case of allergy, IgE-antibodies are found in the blood against food or other environmental allergens, such as house dust, mould or pollen. According to conventional medicine these allergies occur only in people that are genetically predisposed, a condition called atopy. One quarter of the Dutch population has a predisposition to atopic condition. In atopic patients, one or more of the following diseases or symptoms occur: atopic eczema, runny or stuffy nose, conjunctivitis, hay fever or allergic asthma. In addition,  atopic people are more likely to have allergic symptoms such as rashes and hives following the use of certain drug use. Furthermore,  they may also react to infections, dust, clothing, weather influences and other natural phenomena.

The majority (75%) of the population does not have this allergic aptitude. However, food and other allergies can also occur in this group. In these people, antibodies of another type may be raised e.g. IgG or IgA. In order to detect these antibodies, tests have been developed by the KEAC laboratory. These tests have been used for more than thirty years in scientific research and by patients in Europe and beyond, and are sometimes reimbursed by health insurance companies

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The reaction to a food or other substance evolves through certain allergy cells in the mucous membranes (mastocytes) and in the blood (basophilic leucocytes). When an allergen reaches the blood through the intestinal wall, the body produces an antibody as an answer, which matches the allergen like a key to a lock. Antibodies are transported through the blood and attach themselves to the earlier mentioned allergy cells. When the particular food is ingested again these antibodies will attach themselves to the mastocytes. The cell will then produce several substances, amongst which histamine. This substance can let the muscles of the long and intestines contract, it activates certain glands, and it dilates blood vessels and stimulated nerve endings. The result of this may be tightness of the chest, intestinal complaints, coughing up phlegm and mucus, heartburn, redness of the skin, oedema and itching.

When such an allergy exists for more than one food, the causal relationship between the food and the illness is far from easy to determine. An allergy test can provide clarity quickly in such a case. The most important evidence for the existence of a food allergy lies in its scientific evidential value. After a time of abstinence the complaints will immediately start again once the food is ingested again.

Detecting allergic reactions is of great importance, because they deplete the immune system, the stress-regulation system and the hormonal system on the long term. One of the most important symptoms is fatigue (Allergic Fatigue Syndrome). Many secondary complaints may follow, like the piling up of fluid in the middle ear, chronic infections (Candida albicans, fungal infections of the skin, athlete’s foot) and reactive hypoglycaemia (a blood sugar level that fluctuates too strongly). A greater sensitivity to wood protectants, formaldehyde, pesticides etc. also can result.


By abnormalities in the histamine content in cells, allergic reactions can be much stronger as expected. This phenomenon is called hyper reactivity. Allergy is another reaction than that occurs in healthy people; in hyper reactivity it is the same reaction, only much stronger or more violent. This phenomenon can be determined by means of a histamine challenge test on the skin (intradermal test), a histamine provocation test or histamine nose provocation test. In the blood this deviation can be detected by means of a whole blood histamine test.