Hormone profile 24 hour urine

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Description

17-ketosteroid profile

17-ketosteroids are substances that are formed during the breakdown of androgenic steroids: sex hormones and other hormones are excreted by the adrenal gland in men and women and in men by the testis.
The adrenal glands are located on the kidneys as two caps and play a major role in the hormonal system. They produce more than many hormones, including norepinephrine, adrenaline, cortisol, DHEA (dehydroepiandrosterone), progesterone and testosterone. The adrenal glands are responsible for our energy production, sodium-potassium balance, blood pressure, metabolic rate, heart rate, liver function, immune function, blood sugar levels, fat production and how we deal with stress.

In chronic allergic reactions, the stress regulation system of the adrenal gland is repeatedly asked to help. Thanks to this stress-regulation system, even the symptoms of a mild allergic reaction can be completely invisible. In time, the body can get used to this reaction and even need it to feel good (allergic addiction). After a long period of time, the adrenal gland can become exhausted and the compensation disappears, causing the patient to become severely fatigued (allergic fatigue). A malfunction in the adrenal function is characterized in a number of specific symptoms in the initial period:

  • Low blood pressure with dizziness

When someone stands up from sitting or lying down, the systolic blood pressure (the pressure that occurs when the heart pumps the blood into the arteries) rises by ten mm Hg because the blood vessels in the lower body contract to carry blood to the heart, lungs and to supply the brain. This process is made possible by the hormone adrenaline. By people with depleted adrenal glands, the blood vessels are less able to respond to the release of adrenaline due to the lower cortisol content and less epinephrine can be released.

  • Frequent urination a lot of thirst

Someone with a low aldosterone level can go to the toilet fifteen to twenty times daily. The amount that is used is not important. Often one also has to go to the toilet at night. Bed wetting can occur in children.

  • Knit stools lighter in color (occasionally); poor digestion

Delayed blood circulation in the abdominal cavity limits digestion and absorption of important nutrients. Less fluid is extracted from the intestinal contents. Occasionally there is a less compact bowel movement, often with stress.

  • Fatigue attacks; reactive hypoglycaemia

When the depletion of the adrenal glands increases, the blood sugar levels may decrease more. The body responds to hypoglycaemia by pulling in everything that causes the blood sugar level to rise, such as cola, soft drinks, candy, coffee. Sometimes depleted adrenal glands lead to addiction because of the body’s urge to suppress the side effects of hypoglycaemia.

Patients develop a typical daily pattern: they are usually fatigued and are not fitt even after sufficient sleep. In the middle of the morning, people start to wake up first. During the afternoon severe fatigue occurs. Around six o’clock they feel better to get tired again at 21.00 hours. At 23.00 they are fit again and do not sleep but go to bed late.

• Have a taste for salt: The adrenal glands produce the hormone aldosterone, which is a mineralocortioid (steroid hormone that affects the water-salt balance in the body). Aldosterone regulates fluid and electrolytes (sodium, chlorine, potassium and magnesium) in the blood, inside and between the body’s cells. When suffering from depleted adrenal glands, aldosterone production decreases, causing salt wastage. When the salt is excreted by the kidneys, water follows which results in an imbalance of electrolytes and dehydration;
• Sleep disorders: Cortisol production is highest around eight o’clock in the morning and decreases slowly to a low point, which is reached at eleven o’clock in the evening. In the early stages of depleted adrenal glands, the body compensates with a high cortisol level at night. In this case, one has difficulty with de-stressing after a long, hard day’s work and has difficulty sleeping. This reduces the brake sleep (reduced eye movement). This can lead to depression and a reduced energy level the day after. In later stages of hypoadrenia the body produces adrenaline in an attempt to compensate for the low cortisol content. This too leads to insomnia;
• Inflammation: Cortisol and other glucocorticoids (adrenal produced hormones that influence the metabolism of sugars) fall under the category of corticosteroids and its own anti-inflammatory hormones. People who take artificial corticosteroids because the body does not make enough of them, are usually the same people who suffer from depleted adrenal glands.
• Headache: Because the blood supply to the brain is not fully functioning, it does not get enough oxygen and creates headaches
• Unstable blood sugar levels: Adrenal glands and blood sugar levels go hand in hand with each other. Our body must keep blood sugar levels up to standard. When we suffer from stress, adrenaline releases glucose stored in the liver and muscles, which increases blood sugar levels to feed the cells. When the glucose is not absorbed into the cells, the pancreas releases insulin to lower the blood sugar level. This can, however, ensure that the fall is too extreme, which in turn causes stress in the body. As a result, adrenaline is released again, which causes the blood sugar level to rise to normal values again. This process contributes to the exhaustion of the adrenal glands.
• Swelling: While the body tries to keep the balance between fluid and electrolytes, tissues in the body can retain moisture, causing swelling.
• Infections: Heavy and recurrent infections (especially in the respiratory system) often indicate problems with the adrenal glands. The heavier they are, the more they occur or the longer they stay, the greater the chance that depleted adrenal glands contribute to the infection.

  • Headache: Because the blood supply to the brain is not fully functioning, it does not get enough oxygen and creates headaches
    • Unstable blood sugar levels: Adrenal glands and blood sugar levels go hand in hand with each other. Our body must keep blood sugar levels up to standard. When we suffer from stress, adrenaline releases glucose stored in the liver and muscles, which increases blood sugar levels to feed the cells. When the glucose is not absorbed into the cells, the pancreas releases insulin to lower the blood sugar level. This can, however, ensure that the fall is too extreme, which in turn causes stress in the body. As a result, adrenaline is released again, which causes the blood sugar level to rise to normal values again. This process contributes to the exhaustion of the adrenal glands.
    • Swelling: While the body tries to keep the balance between fluid and electrolytes, tissues in the body can retain moisture, causing swelling.
    • Infections: Heavy and recurrent infections (especially in the respiratory system) often indicate problems with the adrenal glands. The heavier they are, the more they occur or the longer they stay, the greater the chance that depleted adrenal glands contribute to the infection.
    • Behavioral and memory problems: Cortisol regulates the electrical activity of neurons in the brain and thus influences behavior, mood and memory. At both high and low levels of cortisol, changes in behavior occur.
    • Hyperpigmentation: This is caused by the fact that ACTH production increases due to the poor functioning of the adrenal glands.

Other symptoms of hypo-adrenia, depleted adrenal, are:
• Mood swings;
• Irritation;
• Difficulties with dealing with stress;
• Low energy level (mental and physical);
• Emotional instability;
• More burden at PMS;
•Depression;
• Poorly functioning immune system;
• Light feeling in the head upon awakening;
• Concentration problems;
• Painful body parts;
• Pull in sugars;
• weak muscles;
•Backache;
•Fatigue;
•Low bloodpressure;
• Dry skin and hair;
• Anxiety attacks;
• Sensitivity to loud sounds;
•Dry eyes;
• Reduced libido;
• Hair loss;
• Contributes to diabetes;
• Contributes to cardiovascular diseases;
• Delayed recovery of diseases.